Morpholino

MO2-wnt5b

ID
ZDB-MRPHLNO-051207-1
Name
MO2-wnt5b
Previous Names
None
Target
Sequence
5' - TGTTTATTTCCTCACCATTCTTCCG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Targets the 3' end of the exon-intron junction of exon 3. Robu et al. report that it is the splice-site–exon 6 splice acceptor (exon 5–6 junction)that is targeted.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 4
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-wnt5b
Expressed Gene Anatomy Figures
cdkn1a Fig. 8 with image from Robu et al., 2007
cp Fig. 6 with image from Kim et al., 2005
cpa5 Fig. 6 with image from Kim et al., 2005
foxa3 Fig. 4 with image from Kim et al., 2005
gata6 Fig. 4 with image from Kim et al., 2005
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Phenotype
Phenotype resulting from MO2-wnt5b
Phenotype Fish Figures
cell migration disrupted, abnormal WT + MO2-wnt5b Fig. 3 with image,  Fig. 5 with image from Kim et al., 2005
convergent extension involved in axis elongation disrupted, abnormal WT + MO2-wnt5b Fig. 3 with image from Kim et al., 2005
endocrine pancreas development disrupted, abnormal WT + MO2-wnt5b Fig. 3 with image,  Fig. 5 with image,  Fig. 6 with image from Kim et al., 2005
extension decreased length, abnormal WT + MO2-wnt5b Fig. 3 with image from Kim et al., 2005
head decreased size, abnormal WT + MO2-wnt5b Fig. 1 with image,  Fig. 3 with image,  Fig. 4 with image from Robu et al., 2007
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Phenotype of all Fish created by or utilizing MO2-wnt5b
Phenotype Fish Conditions Figures
midbrain hindbrain boundary constriction basal region increased width, abnormal AB + MO2-wnt5b + MO4-tp53 control Fig. 2 with image from Gutzman et al., 2018
midbrain hindbrain boundary constriction basal region structure, abnormal AB + MO2-wnt5b + MO4-tp53 control Fig. 2 with image from Gutzman et al., 2018
midbrain hindbrain boundary constriction midbrain-hindbrain boundary morphogenesis process quality, abnormal AB + MO2-wnt5b + MO4-tp53 control Fig. 2 with image from Gutzman et al., 2018
midbrain hindbrain boundary constriction epithelial cell morphogenesis process quality, abnormal AB + MO2-wnt5b + MO4-tp53 control Fig. 2 with image from Gutzman et al., 2018
cell migration disrupted, abnormal WT + MO2-wnt5b standard conditions Fig. 3 with image,  Fig. 5 with image from Kim et al., 2005
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Citations
TSV
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