Gene
foxa3
- ID
- ZDB-GENE-980526-423
- Name
- forkhead box A3
- Symbol
- foxa3 Nomenclature History
- Previous Names
-
- fa11c04
- fc37a08
- fkd2 (1)
- forkhead-2
- wu:fa11c04
- wu:fc37a08
- zf-FKH1
- Zffkh1
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including axial mesoderm morphogenesis; hatching gland development; and nervous system development. Localizes to nucleus. Is expressed in several structures, including axial mesoderm; digestive system; endoderm; germ ring; and hatching gland. Orthologous to human FOXA3 (forkhead box A3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 178 figures from 149 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018122 | Fork head domain conserved site1 |
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Domain | IPR013638 | Fork-head N-terminal |
| Domain | IPR018533 | Forkhead box protein, C-terminal |
| Domain | IPR047366 | Hepatocyte nuclear factor 3-gamma, forkhead domain |
| Family | IPR050211 | Forkhead box domain-containing protein |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Forkhead box domain-containing protein | Forkhead box protein, C-terminal | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Fork-head N-terminal | Hepatocyte nuclear factor 3-gamma, forkhead domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:O73778
|
441 |
Interactions and Pathways
No data available
Plasmids
No data available