FIGURE

Figure 9.

ID

ZDB-FIG-240612-9

Publication

Rahmati et al., 2024 - Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay

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Figure 9.

TA in hNPCs but not in terminally differentiated neuron cells transfected with unstable hAPP695 mRNA. A, Relative APP level in hNPCs transfected with uncapped eGFP (control) or hAPP695 mRNA (N = 9). B, APLP1 and APLP2 levels in hNPCs transfected with uncapped eGFP (control) or hAPP695 mRNA (N = 9). C, Relative APP level in human neuron cells transfected with uncapped eGFP or hAPP695 mRNA (N = 9). D, Relative mRNA level of APLP1 and APLP2 in terminally differentiated neuron cells transfected with uncapped eGFP or hAPP695 mRNA (N = 13). APP in control eGFP transfected cells were set at 1. A–D, n = 3 biologically independent samples. Data are mean + SD. Student's t test was used to calculate p values. *p < 0.05, **p < 0.01, ***p < 0.005, and ****p < 0.0001. ns, nonsignificant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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