FIGURE

Figure 7.

ID

ZDB-FIG-240612-7

Publication

Rahmati et al., 2024 - Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay

Other Figures

All Figure Page

Back to All Figure Page

Figure 7.

Expression of app family genes in wild-type and appb^−/− embryos before and after knocking down NMD factors. A–C, Relative mRNA expression levels of appb, appa, aplp1, and aplp2 in uninjected wild-type embryos (N = 12–15), uninjected appb^−/− (N = 13–15), wild type injected with upf1MO (N = 12), upf2MO (N = 14), upf3a/upf3bMO (N = 13), and appb^−/− injected with upf1MO (N = 11), upf2MO (N = 12), and upf3a/upf3bMO (N = 15). n = 3 biologically independent samples. Data shown as mean + SD. Student's two-tailed t test were used to calculate p values. *p < 0.05, **p < 0.01, ***p < 0.005, and ****p < 0.0001. ns, nonsignificant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ eNeuro