FIGURE

Fig. 2

ID

ZDB-FIG-140902-20

Publication

Pfefferli et al., 2014 - Specific NuRD components are required for fin regeneration in zebrafish

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Fig. 2

Specific NuRD component orthologs are expressed in the blastema of regenerating fins. (A) Quantitative real-time-PCR analyses of hdac1, mta1, mta2, mta3, rbb4, rbb4l, mbd3a, mbd3b, and mbd2 mRNA in regenerating adult caudal fins at 1 and 3 dpa relative to control fins at 0 hpa. Error bars represent the SEM. *P < 0.001 (B-D) In situ hybridization with hdac1 (B), rbb4(C), and mta2 (D), antisense probes on cryosections of regenerating adult caudal fins at 3 dpa. Dashed lines indicate the amputation plane. (E-G) Whole-mount in situ hybridization with hdac1 (E), rbb4 (F) and mta2 (G) antisense probes in 1 dpa larval tails. Scale bar: 100 μm.

Expression Data

Genes:	hdac1 mbd2 mbd3a mbd3b mta1 mta2 mta3 rbb4l rbbp4
Fish:	AB
Condition:	amputation: fin
Anatomical Terms:	blastema caudal fin regenerating fin regenerating fin mesenchymal cell
Stage Range:	Protruding-mouth to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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