Gene
mbd2
- ID
- ZDB-GENE-030131-9049
- Name
- methyl-CpG binding domain protein 2
- Symbol
- mbd2 Nomenclature History
- Previous Names
-
- wu:fa97f06
- zgc:111862
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have methyl-CpG binding activity. Predicted to be involved in methylation-dependent chromatin silencing and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pfefferli et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DNA-binding domain superfamily | Methyl-CpG-binding domain protein 2/3, p55-binding region | Methyl-CpG binding protein 2/3, C-terminal domain | Methyl-CpG DNA binding |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZTV3
|
256 |
Interactions and Pathways
No data available
Plasmids
No data available