Gene

mta1

ID

ZDB-GENE-131121-353

Name

metastasis associated 1

Symbol

mta1 Nomenclature History

Previous Names

si:dkeyp-84b10.1

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have RNA polymerase II repressing transcription factor binding activity; histone deacetylase binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including double-strand break repair; histone deacetylation; and response to ionizing radiation. Predicted to localize to NuRD complex. Orthologous to human MTA1 (metastasis associated 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Pfefferli et al., 2014

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mta1 Human Ortholog

No data available

Associated With mta1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000679	Zinc finger, GATA-type
Domain	IPR000949	ELM2 domain
Domain	IPR001005	SANT/Myb domain
Domain	IPR001025	Bromo adjacent homology (BAH) domain
Domain	IPR017884	SANT domain
Domain	IPR035170	Metastasis-associated protein MTA1, R1 domain
Family	IPR040138	Mesoderm induction early response protein/metastasis-associated protein
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR043151	Bromo adjacent homology (BAH) domain superfamily

Domain Details Per Protein

Protein	Length	Bromo adjacent homology (BAH) domain	Bromo adjacent homology (BAH) domain superfamily	ELM2 domain	Homedomain-like superfamily	Mesoderm induction early response protein/metastasis-associated protein	Metastasis-associated protein MTA1, R1 domain	SANT domain	SANT/Myb domain	Zinc finger, GATA-type
UniProtKB:E7FC29 InterPro	615
UniProtKB:A0A2R8RTX5 InterPro	617

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mta1-201 (1) Ensembl	Ensembl	3,046 nt	Select Tool
mRNA	mta1-204 (1) Ensembl	Ensembl	1,899 nt	Select Tool ZFIN BLAST
ncRNA	mta1-002 (1) Ensembl	Ensembl	730 nt	Select Tool
ncRNA	mta1-003 (1) Ensembl	Ensembl	771 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations