Gene

mbd3a

ID
ZDB-GENE-030131-9077
Name
methyl-CpG binding domain protein 3a
Symbol
mbd3a Nomenclature History
Previous Names
  • wu:fa98f07
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have methyl-CpG binding activity. Predicted to be involved in methylation-dependent chromatin silencing and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in blastomere and pharyngeal arch 3-7 skeleton. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Fillatre et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mbd3a Human Ortholog
No data available
Associated With mbd3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001739 Methyl-CpG DNA binding
Domain IPR025884 Methyl-CpG binding protein 2/3, C-terminal domain
Domain IPR032343 Methyl-CpG-binding domain protein 2/3, p55-binding region
Homologous_superfamily IPR016177 DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding domain superfamily Methyl-CpG-binding domain protein 2/3, p55-binding region Methyl-CpG binding protein 2/3, C-terminal domain Methyl-CpG DNA binding
UniProtKB:Q7ZTV2 241
UniProtKB:Q6TGX7 273
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mbd3a-201 (1) Ensembl 1,829 nt
mRNA mbd3a-202 (1) Ensembl 998 nt
mRNA mbd3a-203 (1) Ensembl 830 nt
mRNA mbd3a-204 (1) Ensembl 1,688 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations