FIGURE

Fig. 1

ID

ZDB-FIG-140902-19

Publication

Pfefferli et al., 2014 - Specific NuRD components are required for fin regeneration in zebrafish

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Fig. 1

One of the three Mi-2 orthologs, chd4a, is specifically induced in the blastema during fin regeneration. (A) Quantitative real-time-PCR analysis of chd4a, chd4b, and chd3 mRNA in regenerating adult caudal fins at 1 day post-amputation (dpa) and 3 dpa relative to control fins at 0 hours post-amputation (hpa). Error bars represent the SEM. *P < 0.001 (B-D) In situ hybridization with chd4a (B), chd4b (C), and chd3 (D) mRNA antisense probes on cryosections of regenerating adult caudal fins at 3 dpa. Dashed lines indicate the amputation plane. (E-G) Whole-mount in situ hybridization with chd4a (E), chd4b(F), and chd3(G) antisense probes in 1 dpa larval tails. Scale bar: 100 μm.

Expression Data

Genes:	chd3 chd4a chd4b
Fish:	AB
Condition:	amputation: fin
Anatomical Terms:	blastema caudal fin regenerating fin regenerating fin
Stage Range:	Protruding-mouth to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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