FIGURE
Fig. S5
Fig. S5
Med12 appears to regulate sox17 expression. Wild-type, and bon, cas/sox32, or gata5 mRNA-injected embryos with or without med12 MO were analyzed between 70 and 80% epiboly for sox17 (A, B, C, G, H, I, M, N, O) or cas/sox32 (D, E, F, J, K, L) expression. The ability of Gata5, Bon or Cas to up-regulate sox17 expression (B, H, N) appears to be affected by the injection of med12 MO (C, I, O). However, cas expression in these overexpression assays (E, K) appears not to be affected by med12 MO injections (F, L). All images are dorsal views, anterior to the top. |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage Range: | Shield to 75%-epiboly |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 317(2), Shin, C.H., Chung, W.S., Hong, S.K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J., and Stainier, D.Y., Multiple roles for Med12 in vertebrate endoderm development, 467-479, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.