Image
|
Figure Caption
Fig. S5 Med12 appears to regulate sox17 expression. Wild-type, and bon, cas/sox32, or gata5 mRNA-injected embryos with or without med12 MO were analyzed between 70 and 80% epiboly for sox17 (A, B, C, G, H, I, M, N, O) or cas/sox32 (D, E, F, J, K, L) expression. The ability of Gata5, Bon or Cas to up-regulate sox17 expression (B, H, N) appears to be affected by the injection of med12 MO (C, I, O). However, cas expression in these overexpression assays (E, K) appears not to be affected by med12 MO injections (F, L). All images are dorsal views, anterior to the top.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 317(2), Shin, C.H., Chung, W.S., Hong, S.K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J., and Stainier, D.Y., Multiple roles for Med12 in vertebrate endoderm development, 467-479, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.