FIGURE

Fig. S2

ID

ZDB-FIG-080516-24

Publication

Shin et al., 2008 - Multiple roles for Med12 in vertebrate endoderm development

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Fig. S2

shr is required for ventral pancreas development. Confocal projections of wild-type and shr^s435 mutant larvae in the Tg(fabp1a:dsRed, elastase:GFP; insulin:dsRed) line at 96 hpf. (A, A′) shr^s435 mutant larvae show multiple Tg(elastase: GFP)-positive ventral pancreatic buds (white arrowheads), and defective elongation of the ventral pancreatic tail (white arrow). Despite defective hepatic differentiation, a population of liver cells expresses DsRed in the mutant larvae. All images are ventral views, anterior to the top.

Expression Data

Genes:	DsRed GFP
Fish:	gz2Tg; gz4Tg; m1018Tg med12^s435/s435; gz2Tg; gz4Tg; m1018Tg
Anatomical Terms:	endocrine pancreas exocrine pancreas liver
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	med12^s435/s435; gz2Tg; gz4Tg; m1018Tg
Observed In:	endodermal cell fate specification exocrine pancreas exocrine pancreas development liver
Stage:	Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 317(2), Shin, C.H., Chung, W.S., Hong, S.K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J., and Stainier, D.Y., Multiple roles for Med12 in vertebrate endoderm development, 467-479, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.