Figure 4—figure supplement 1.

Ectopic Sema7Asec diffusive cues induce aberrant sensory neurite extension.

(A-A") In a micrograph of an ectopically expressing Sema7Asec (orange) larva, the sensory arbors (magenta) extend multiple axonal projections (arrowheads) that reenter the lateral-line nerve while following an ectopic Sema7A source. Maximal-intensity projections of the sensory arbors and the ectopically expressing Sema7A cells (white dashed line) are shown in A' and A", respectively. (B-B") Micrographs depict three individual incidents of ectopic sema7asec (orange) integrations that occurred distant from neuromasts. In each case, a set of myofibers expresses the ectopic Sema7Asec protein that induces neurite extensions (arrowheads) from the lateral-line nerve (magenta) toward itself. Scale bars, 20 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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