FIGURE

Fig. S2

ID

ZDB-FIG-181024-12

Publication

Xu et al., 2018 - Fox proteins are modular competency factors for facial cartilage and tooth specification

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Fig. S2

Regulation of foxc1b and foxd1 arch expression

Expression of foxc1b (A) and foxd1 (B) in green, relative to dlx2a+ CNCs (red) of the first two arches. Similar to foxc1a in Figure 1, foxc1b and foxd1 expression is expanded by Shha misexpression, inhibited by Bmp4 and Fgf3 misexpression, and reduced in edn1 but not jag1b mutants. Embryos doubly transgenic for hsp70l:Gal4 and UAS:shha, UAS:bmp4, or UAS:fgf3 were subjected to a heatshock from 20-24 hpf to induce ligand expression throughout embryos. Numbers indicate proportion of animals showing the displayed patterns. Scale bars = 25 μm.

Expression Data

Genes:	dlx2a foxc1b foxd1
Fish:	edn1^{tf216b/tf216b} jag1b^b1105/b1105 el137Tg; kca4Tg el49Tg; kca4Tg el688Tg; kca4Tg
Condition:	heat shock
Anatomical Terms:	pharyngeal arch 1 pharyngeal arch 1 cranial neural crest pharyngeal arch 2 pharyngeal arch 2 cranial neural crest
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	edn1^{tf216b/tf216b} el137Tg; kca4Tg el49Tg; kca4Tg el688Tg; kca4Tg
Condition:	heat shock
Observed In:	pharyngeal arch 1 pharyngeal arch 2
Stage:	Prim-25

Phenotype Detail

Acknowledgments

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