Gene
dlx2a
- ID
- ZDB-GENE-980526-212
- Name
- distal-less homeobox 2a
- Symbol
- dlx2a Nomenclature History
- Previous Names
-
- dlx-2
- dlx2
- zgc:110518
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including neural crest cell development; pharyngeal system development; and skeletal system development. Predicted to localize to nucleus. Is expressed in several structures, including brain; cranial cartilage; neural crest; pectoral fin bud; and pharyngeal arch. Orthologous to human DLX2 (distal-less homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 431 figures from 293 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu96 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000047 | Helix-turn-helix motif |
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR020479 | Homeodomain, metazoa |
| Domain | IPR022135 | Distal-less-like homeobox protein, N-terminal domain |
| Family | IPR050460 | Distal-less homeobox transcription factors |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Distal-less homeobox transcription factors | Distal-less-like homeobox protein, N-terminal domain | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F6NKE2
|
274 | |||||||
|
UniProtKB:P50574
|
270 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available