FIGURE
Fig. 5
Fig. 5
Downregulation of cldn5a resulted in defective KV lumen in zebrafish. (A—F) Maximum intensity projection images of ZO-1 (grey) and sox17:egfp-positive KV cells (green) in 6 ss, 8 ss and 10 ss embryos. Representative images of the DFC control morphants (A—C) and DFC cldn5a morphants (D—F). (G) Statistical box and whisker graph (DFC control morphants at 6 ss; n = 20, DFC control morphants at 8 ss; n = 31, DFC control morphants at 10 ss; n = 15, DFC cldn5a morphants at 6 ss; n = 28, DFC cldn5a morphants at 8 ss; n = 21, DFC cldn5a morphants at 10 ss; n = 18). Scale bar: 20 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | 5-9 somites |
Phenotype Detail
Acknowledgments
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