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Fig. 5
Downregulation of cldn5a resulted in defective KV lumen in zebrafish.
(A—F) Maximum intensity projection images of ZO-1 (grey) and sox17:egfp-positive KV cells (green) in 6 ss, 8 ss and 10 ss embryos. Representative images of the DFC control morphants (A—C) and DFC cldn5a morphants (D—F). (G) Statistical box and whisker graph (DFC control morphants at 6 ss; n = 20, DFC control morphants at 8 ss; n = 31, DFC control morphants at 10 ss; n = 15, DFC cldn5a morphants at 6 ss; n = 28, DFC cldn5a morphants at 8 ss; n = 21, DFC cldn5a morphants at 10 ss; n = 18). Scale bar: 20 μm.
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