FIGURE

Fig. 1

ID

ZDB-FIG-171101-14

Publication

Felber et al., 2015 - Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation

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Fig. 1

FGF signalling is required for ossification and osteoblast maturation.

(A-D) Continuous inhibition of FGF signalling from 48hpf to 120hpf in hs:dnfgfr1 larvae results in loss of ossification (B) but cartilage formation is relatively unaffected (D). (E-H) Expression of mature osteoblast markers col1a2 and col10a1 is severely reduced in hs:dnfgfr1 larvae (F,H). High magnification images of the opercle are shown to the right of panels E-H. Abbreviations: bs = branchiostegal ray, cl = cleithrum, op = opercle. Scale bar = 200μM.

Expression Data

Genes:	col1a2 col10a1a
Fish:	pd1Tg/+
Condition:	heat shock
Anatomical Terms:	opercle opercle osteoblast
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pd1Tg/+
Condition:	heat shock
Observed In:	mandibular arch skeleton opercle opercle osteoblast ossification
Stage:	Day 5

Phenotype Detail

Acknowledgments

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