FIGURE

Fig. 1

ID

ZDB-FIG-151120-11

Publication

Won et al., 2015 - Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas

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Fig. 1

lnx2a is expressed in the ventral pancreas during early pancreas specification. Lateral views (A and I), dorsal views (B–E), and ventral views (F–H). (A) lnx2a transcripts (blue) are detected in regions of the endoderm (arrow), forebrain (arrowhead), and the spinal cord at 24 hpf. Expression of pdx1 (B, D, and G), ins (C, E, and I) and foxa3 (F) are in red. lnx2a expression is observed in the antero-ventral part of pdx1-positive pancreas precursors at 21 (B) and 26 (D) hpf, but excluded from β-cells (ins⁺) in the dorsal pancreas at 21 (C), 26 (E), and 48 (I) hpf. At 48 hpf, lnx2a expression is detected in the ventral pancreas but not in the intestine, swim bladder, or liver (F–H). SB, swim bladder; In, intestine; Li, liver; Pa, pancreas; VP, ventral pancreas. (Scale bars: 50 µm.)

Expression Data

Genes:	foxa3 ins lnx2a pdx1 ptf1a
Fish:	AB
Anatomical Terms:	anterior pancreatic bud endoderm exocrine cell forebrain pancreas pancreas primordium pancreas primordium antero-ventral region pancreas primordium dorsal region posterior pancreatic bud spinal cord
Stage Range:	20-25 somites to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA