FIGURE
Fig. 5
- ID
- ZDB-FIG-151120-15
- Publication
- Won et al., 2015 - Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas
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Fig. 5
Ventral pancreas defects in lnx2aΔ329 mutant and lnx2a-MO–injected embryos can be rescued by knockdown of Numb. (A) The translation blocking MO for Numb (5 ng) was injected into WT, lnx2aΔ329-, and lnx2a-MO–injected embryos, and pancreatic phenotype was examined at 60 hpf. (Scale bar: 50 µm.) (B) Quantification of pancreatic defects by analysis of ptf1a expression. Exocrine pancreas defects were substantially rescued by knockdown of Numb; numb-MO had little effect in WT embryos. (C) Immunoblotting of embryo extracts with Numb antibody shows the efficiency of the numb-MO. |
Expression Data
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| Stage: | Pec-fin |
Expression Detail
Antibody Labeling
Phenotype Data
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| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Pec-fin |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA