FIGURE

Fig. 4

ID

ZDB-FIG-140506-49

Publication

Pavlou et al., 2014 - Pleiotropic effects of Sox2 during the development of the zebrafish epithalamus

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Fig. 4

C) Tg(aanat2:GFP) drives GFP expression in the pineal PhRs. (B) Isl1 labels the pineal cells. (D–F) Knockdown of sox2 results in increased number of PhRs. (G) The average number of PhRs in control (purple bar) and sox2 morphants (orange bar). (H–J) Tg(elavl3:GFP) drives GFP expression specifically in the PNs. (K–M) The knockdown of sox2 does not affect the number of PNs. (N) The average number of PNs in controls (purple bar) and sox2 morphants (orange bar) does not significantly differ. Confocal maximum projections of 28 hpf embryos, scale bars = 25 μm, error bars represent ± standard error, ** = p-value <0.001 (MWU test). See also Figure S4.

Expression Data

Gene:	EGFP
Antibody:	Ab2-isl
Fish:	knu3Tg y8Tg knu3Tg + MO6-sox2 y8Tg + MO6-sox2
Knockdown Reagent:	MO6-sox2
Anatomical Terms:	pineal complex neuron pineal complex photoreceptor cell
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y8Tg + MO6-sox2
Knockdown Reagent:	MO6-sox2
Observed In:	pineal complex photoreceptor cell
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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