FIGURE

Fig. S2

ID
ZDB-FIG-120127-15
Publication
Wong et al., 2012 - Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish
Other Figures
All Figure Page
Back to All Figure Page
Fig. S2

Inhibition of Notch signaling by DAPT treatment does not significantly affect endocardial morphogenesis while arterial-venous differentiation is perturbed.

(A-D) Endocardial kdrl (arrows, A,B) and NFATc1 (arrows, C,D) expression at the 18-somite and 24 hpf stages, respectively, is not affected in DAPT-treated embryos (B,D) compared to DMSO-treated controls (A,C). (E,F) Venous flt4 expression at 24 hpf (arrow) is expanded in DAPT treated embryos (F) compared to DMSO-treated controls (E).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 361(2), Wong, K.S., Rehn, K., Palencia-Desai, S., Kohli, V., Hunter, W., Uhl, J.D., Rost, M.S., and Sumanas, S., Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish, 377-91, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.