Publication	Data		Fish	Anatomy
Korzh et al., 2021	Fig. 1		smob641/b641; gz2Tg	pancreas deformed, abnormal pancreas duplicated, abnormal pancreas EGFP expression spatial pattern, abnormal
	Fig. 2		smob641/b641; gz15Tg	exocrine pancreas EGFP expression spatial pattern, abnormal gut decreased diameter, abnormal liver DsRed expression spatial pattern, abnormal liver duplicated, abnormal pancreas duplicated, abnormal
Lu et al., 2020	Fig. 8		smohi1640Tg/hi1640Tg	trunk curved ventral, abnormal
Osborn et al., 2020	Fig. 1		smob641/b641	adaxial cell ptch2 expression absent, abnormal segmental plate adaxial cell myod1 expression absent, abnormal somite adaxial cell myod1 expression absent, abnormal
Hartwell et al., 2019	Fig 1		smohi1640Tg/hi1640Tg	inner ear has extra parts of type anterior macula, abnormal inner ear has extra parts of type lateral crista, abnormal inner ear lacks all parts of type posterior macula, abnormal inner ear morphogenesis decreased process quality, abnormal inner ear posterior region anteriorized, abnormal otolith fused with otolith, abnormal sagitta decreased size, abnormal sagitta mislocalised ventrally, abnormal
Hoshijima et al., 2019	Fig. 3		smohi1640Tg/hi1640Tg	fast muscle cell absent, abnormal muscle pioneer absent, abnormal slow muscle cell absent, abnormal
Pereira Piedade et al., 2019	Fig. 3.		smohi1640Tg/hi1640Tg	central nervous system siah1 expression decreased amount, abnormal whole organism pax2a expression decreased amount, abnormal whole organism siah1 expression decreased amount, abnormal
Yin et al., 2018	Fig. 7		smob641/b641	fast muscle cell skeletal muscle tissue development delayed, abnormal slow muscle cell absent, abnormal
Han et al., 2017	Fig. 5		AB + MO8-smo	adaxial cell ptch2 expression decreased amount, abnormal slow muscle cell morphology, abnormal somite ab1-eng labeling decreased amount, abnormal somite U-shaped, abnormal
Pickering et al., 2017	Fig. 3		smohi1640Tg/hi1640Tg	central nervous system anterior region lama1 expression decreased amount, abnormal pronephric duct opening lama1 expression decreased amount, abnormal segmental plate lama1 expression decreased amount, abnormal
Roberson et al., 2017	Fig. 4		smohi1640Tg/hi1640Tg	dorsal habenular nucleus cxcr4b expression absent, abnormal dorsal habenular nucleus dbx1b expression absent, abnormal
Halluin et al., 2016	Fig. 4		smohi229Tg/hi229Tg	epithalamus cxcr4b expression absent, abnormal eye cxcr4b expression decreased amount, abnormal habenula pou4f1 expression absent, abnormal
Li et al., 2016	Fig. S5		smohi1640Tg/hi1640Tg	somite ubr3 expression absent, abnormal
McCarthy et al., 2016	Fig. 10		smob577/b577	chondrocyte col2a1a expression absent, abnormal
Stiff et al., 2016	Fig. 3		smohi1640Tg/hi1640Tg	Kupffer's vesicle motile cilium decreased length, abnormal
Zhao et al., 2016	Fig. 5		smohi1640Tg/hi1640Tg	brain nkx2.2a expression decreased amount, abnormal brain olig2 expression decreased amount, abnormal brain ptch2 expression decreased amount, abnormal neural tube nkx2.2a expression absent, abnormal neural tube olig2 expression absent, abnormal neural tube ptch2 expression absent, abnormal
Boyd et al., 2015	Fig. 1		smob641/b641	diencephalon ventral region disc1 expression decreased amount, abnormal diencephalon ventral region disc1 expression decreased distribution, abnormal hindbrain axial region disc1 expression decreased amount, abnormal hindbrain dorso-lateral region disc1 expression decreased distribution, abnormal
	Fig. 3		smob641/b641	whole organism disc1 expression absent, abnormal
Wheway et al., 2015	Fig. 7		smob641/b641	brain hydrocephalic, abnormal eye decreased size, abnormal otolith non-functional, abnormal whole organism anterior-posterior axis curved ventral, abnormal
Alvers et al., 2014	Fig. 5		smos294/s294; pd1034Tg ,   smos294/s294	intestine anatomical space increased amount, abnormal intestine anatomical space trabecular, abnormal intestine epithelial tube morphogenesis disrupted, abnormal
Kondrychyn et al., 2013	Fig. s1		smob641/b641; sqet33Et	roof plate spinal cord region cell projection decreased length, abnormal spinal cord morphology, abnormal
Maurya et al., 2013	Fig. 3		smob641/b641	muscle pioneer ab1-eng labeling absent, abnormal muscle pioneer absent, abnormal slow muscle cell prox1a expression absent, abnormal
	Fig. 8		smob641/b641	spinal cord ventral region olig2 expression absent, abnormal
Reimer et al., 2013	Fig. 5		smob577/b577	spinal cord motor neuron decreased amount, abnormal
Milla et al., 2012	Fig. 4		smohi1640Tg/hi1640Tg	notochord neo1a expression absent, abnormal retinal ganglion cell layer neo1a expression absent, abnormal
	Fig. 5		smohi1640Tg/hi1640Tg	eye myca expression absent, abnormal liver myca expression decreased amount, abnormal optic tectum myca expression absent, abnormal
Wong et al., 2012	Fig. 7		WT + MO4-smo	endocardium development disrupted, abnormal
Yin et al., 2012	Fig. 6		smob641/+	pancreas morphology, abnormal swim bladder development disrupted, abnormal swim bladder disorganized, abnormal
Evron et al., 2011	Fig. 5		smos294/+	embryo development disrupted, abnormal somite disorganized, abnormal trunk curved, abnormal
	Fig. 6		smos294/+	muscle pioneer absent, abnormal slow muscle cell decreased amount, abnormal
Klüver et al., 2011	Fig. S5		smob577/b577	muscle pioneer hspb9l expression absent, abnormal
Osborn et al., 2011	Fig. 1		smob641/b641	segmental plate anterior region lacks all parts of type adaxial cell, abnormal skeletal muscle tissue development disrupted, abnormal slow muscle cell aplastic, abnormal
Untergasser et al., 2011	Fig. 4		smom841/m841	central nervous system dkk3a expression decreased amount, abnormal
	Fig. 6		smom841/m841	islet dkk3b expression absent, abnormal
Barresi et al., 2010	Fig. 4		smohi229Tg/hi229Tg (AB/TU)	hindbrain anterior/posterior pattern specification disrupted, abnormal hindbrain radial glial cell morphology, abnormal
	Fig. 5		smohi229Tg/hi229Tg (AB/TU)	spinal cord lacks all parts of type ventricular zone radial glial cell, abnormal
	Fig. 6		smohi229Tg/hi229Tg (AB/TU)	spinal cord glial cell (sensu Vertebrata) mislocalised, abnormal
	text only		smohi229Tg/hi229Tg (AB/TU)	anterior commissure astrocyte mislocalised, abnormal anterior commissure morphology, abnormal cranial nerve II commissural neuron axon guidance disrupted, abnormal postoptic commissure astrocyte mislocalised, abnormal postoptic commissure morphology, abnormal
Lamont et al., 2010	Fig. S7		smonv122/nv122	ventral mesenchyme physical object quality, abnormal
Schwend et al., 2010	Fig. 1		smob641/b641	post-vent region curved ventral, abnormal somite U-shaped, abnormal
Teoh et al., 2010	Fig. 5		smounspecified/unspecified	swim bladder physical object quality, abnormal
Aanstad et al., 2009	Fig. 1		smos294/s294 ,   smohi1640Tg/hi1640Tg	muscle cell differentiation process quality, abnormal muscle pioneer absent, abnormal slow muscle cell absent, abnormal slow muscle cell decreased amount, abnormal
	Fig. 2		smos294/s294 ,   smohi1640Tg/hi1640Tg	muscle cell differentiation process quality, abnormal muscle pioneer absent, abnormal slow muscle cell absent, abnormal slow muscle cell decreased amount, abnormal
Feijoo et al., 2009	Fig. 6		smob577/b577	forebrain physical object quality, abnormal midbrain hindbrain boundary physical object quality, abnormal
Parkin et al., 2009	Fig. 3		smob577/b577	proctodeum atretic, abnormal proctodeum malformed, abnormal
Paulus et al., 2009	Fig. 3		smob641/b641 (AB)	axon guidance disrupted, abnormal Rohon-Beard neuron morphology, abnormal sensory neuron mislocalised, abnormal sensory neuron morphology, abnormal
Sanek et al., 2009	Fig. 1		smob641/b641	smoothened signaling pathway disrupted, abnormal
	Fig. 3		smob641/b641	smoothened signaling pathway disrupted, abnormal
Snow et al., 2009	Fig. 4		smounspecified/unspecified	myoseptum broken, abnormal myotome morphology, abnormal
Wilson et al., 2009	Fig. 3		smohi1640Tg	smoothened signaling pathway disrupted, abnormal
Winata et al., 2009	Fig. 4		smob641/b641; sqet332Et ,   smob641/b641	mesothelial cell decreased amount, abnormal mesothelial cell distributed, abnormal smooth muscle aplastic, abnormal swim bladder aplastic, abnormal swim bladder formation arrested, abnormal
Chung et al., 2008	Fig. 2		smohi1640Tg/hi1640Tg; zf5Tg	liver development disrupted, abnormal liver morphology, abnormal pancreas development disrupted, abnormal pancreas morphology, abnormal
	Fig. S1		smohi1640Tg/hi1640Tg	pancreas development disrupted, abnormal
Elworthy et al., 2008	Fig. 7		smob641/b641	slow muscle cell decreased size, abnormal
García-Lecea et al., 2008	Fig. 5		smob641/b641; sqet33e20Et	tela chorioidea cell decreased amount, abnormal tela chorioidea cell fragility, abnormal tela chorioidea decreased size, abnormal tela chorioidea hypoplastic, abnormal tela chorioidea morphology, abnormal
	Fig. S2		smob641/b641; sqet33e20Et	ventricular system apoptotic, abnormal
Ke et al., 2008	Fig. 4		smob641/b641	oligodendrocyte differentiation disrupted, abnormal
	Fig. 6		smob641/b641	floor plate formation disrupted, abnormal
Kishi et al., 2008	text only		smohi229Tg/hi229Tg ,   smohi2329bTg/hi2329bTg ,   smohi1640Tg/hi1640Tg	cellular senescence increased magnitude, abnormal eye decreased distance eye, abnormal eye decreased size, abnormal lateral floor plate aplastic, abnormal pericardium edematous, abnormal secondary motor neuron absent, abnormal somite U-shaped, abnormal trunk curved ventral, abnormal whole organism decreased thickness, abnormal whole organism lethal (sensu genetics), abnormal yolk grey, abnormal yolk morphology, abnormal
McFarland et al., 2008	Fig. 3		smob641/b641	cerebellum physical object quality, abnormal spinal cord physical object quality, abnormal
Pendeville et al., 2008	Fig. 6		smob641/b641	vasculogenesis disrupted, abnormal
Sanek et al., 2008	Fig. 6		smob641/b641	diencephalon development disrupted, abnormal ventral thalamus decreased size, abnormal
Thomas et al., 2008	Fig. 1		smob577/b577 ,   smob577/b577 ,   smob577/b577; f2Tg ,   smob577/b577; f2Tg/+	atrium cardiac muscle cell decreased amount, abnormal cardiac ventricle cardiac muscle cell decreased amount, abnormal heart cardiac muscle cell decreased amount, abnormal heart decreased size, abnormal heart malformed, abnormal
	Fig. 2		smob577/b577	heart primordium cardiac muscle myoblast decreased amount, abnormal heart primordium mesodermal cell decreased amount, abnormal
	Fig. 7		smob577/b577	common cardinal vein increased width, abnormal
Yamaguchi et al., 2008	Fig. 2		smob577/b577	eye morphology, abnormal
Hadzhiev et al., 2007	Fig. 4		smob641/b641; sb15Tg	caudal fin melanocyte mislocalised, abnormal
Loucks et al., 2007	Fig. 1		smob641/b641	eye fused with eye, abnormal post-vent region curved ventral, abnormal
Robu et al., 2007	Fig. 1		WT + MO4-smo + MO4-tp53 ,   WT + MO4-smo	head decreased size, abnormal nervous system apoptotic, abnormal somite shape, abnormal spinal cord curved, abnormal
	Fig. 2		WT + MO4-smo	nervous system apoptotic, abnormal
Schibler et al., 2007	Fig. 1		smojj392/jj392 (AB)	inner ear decreased size, abnormal inner ear development paedomorphic growth, abnormal lapillus decreased size, abnormal sagitta decreased size, abnormal
	Fig. 3		smojj392/jj392 (AB)	pillar of the anterior semicircular canal increased thickness, abnormal pillar of the anterior semicircular canal shape, abnormal
	text only		smojj392/jj392 (AB)	eye fused with eye, abnormal macula fused with macula, abnormal otolith decreased size, abnormal otolith mislocalised, abnormal whole organism curved, abnormal
Feng et al., 2006	Fig. 2		smob641/b641 (AB)	muscle cell differentiation decreased occurrence, abnormal somite has extra parts of type muscle precursor cell, abnormal
Phenotype Annotation (1994-2006)	Fig. for (b577)		smob577/b577 (AB)	myoseptum quality, abnormal post-vent region quality, abnormal somite quality, abnormal whole organism shape, abnormal
	Fig. for (b641)		smob641/b641 (AB)	brain quality, abnormal floor plate quality, abnormal forebrain quality, abnormal nervous system quality, abnormal
	Fig. for (hi1640)		smohi1640Tg	brain quality, abnormal eye quality, abnormal forebrain quality, abnormal midbrain quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal sensory system quality, abnormal surface structure quality, abnormal
	Fig. for (hi229)		smohi229Tg	brain quality, abnormal eye quality, abnormal forebrain quality, abnormal midbrain quality, abnormal nervous system quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal sensory system quality, abnormal surface structure quality, abnormal
	Fig. for (hi2329b)		smohi2329bTg	whole organism quality, abnormal
	Fig. for (m841)		smom841	brain quality, abnormal
Amsterdam et al., 2004	text only		smohi229Tg/hi229Tg	eye decreased distance eye, abnormal eye decreased size, abnormal lateral floor plate aplastic, abnormal pericardium edematous, abnormal secondary motor neuron absent, abnormal somite U-shaped, abnormal trunk decreased thickness, abnormal whole organism curved ventral, abnormal whole organism viability, abnormal yolk grey, abnormal yolk swollen, abnormal
Cheesman et al., 2004	Fig. 6		smob641/b641 (AB)	positive regulation of DNA-templated transcription disrupted, abnormal
Hammond et al., 2003	Fig. 3		smob641/b641 (AB)	anterior macula increased size, abnormal inner ear wholly anteriorized, abnormal otolith decreased size, abnormal posterior macula aplastic, abnormal
	Fig. 4		smob641/b641 (AB)	pars superior ear has extra parts of type anterior crista, abnormal
	text only		smob641/b641 (AB)	inner ear wholly anteriorized, abnormal
Golling et al., 2002	Fig. 1		smohi229Tg/hi229Tg	eye fused with eye, abnormal somite U-shaped, abnormal
Park et al., 2002	Fig. 7		smob641/b641	oligodendrocyte development disrupted, abnormal spinal cord lacks all parts of type oligodendrocyte, abnormal
Chen et al., 2001	Fig. 1		smohi229Tg ,   smohi1640Tg	anterior commissure absent, abnormal caudal commissure absent, abnormal cleithrum hypoplastic, abnormal eye fused with eye, abnormal head decreased size, abnormal mandibular arch skeleton aplastic, abnormal optic chiasm malformed, abnormal pectoral fin aplastic, abnormal pharyngeal arch 3-7 aplastic, abnormal postoptic commissure absent, abnormal
	Fig. 4		smohi229Tg ,   smohi1640Tg	lateral floor plate absent, abnormal medial floor plate broken, abnormal
	Fig. 5		smohi229Tg ,   smohi1640Tg	primary motor neuron absent, abnormal primary motor neuron axon disorganized, abnormal primary motor neuron decreased amount, abnormal secondary motor neuron decreased amount, abnormal
	Fig. 6		smohi229Tg ,   smohi1640Tg	dopaminergic neuron decreased amount, abnormal
	Fig. 7		smohi229Tg ,   smohi1640Tg	heart malformed, abnormal
	Fig. 8		smohi229Tg ,   smohi1640Tg	cell death increased process quality, abnormal cell population proliferation decreased process quality, abnormal
Lewis et al., 2001	Fig. 1		smob641/b641 (AB)	primary motor neuron decreased amount, abnormal
	Fig. 3		smob641/b641 (AB)	primary motor neuron decreased amount, abnormal
	Table 1		smob641/b641 (AB)	primary motor neuron decreased amount, abnormal somite U-shaped, abnormal
Roy et al., 2001	Fig. 1		smob641/b641 (AB)	endocrine cell decreased amount, abnormal pancreas development disrupted, abnormal pancreas primordium hypoplastic, abnormal
	Fig. 3		smob641/b641 (AB)	endocrine cell decreased amount, abnormal pancreas development disrupted, abnormal pancreas primordium hypoplastic, abnormal
	Fig. 4		smob641/b641 (AB)	liver development process quality, abnormal liver morphology, abnormal
Varga et al., 2001	Fig. 1		smob641/b641 (AB)	floor plate development decreased process quality, abnormal somite lacks all parts of type horizontal myoseptum, abnormal somite U-shaped, abnormal whole organism curved ventral, abnormal
	Fig. 2		smob641/b641 (AB)	caudal fin lacks all parts of type primary motor neuron, abnormal lateral floor plate absent, abnormal secondary motor neuron absent, abnormal spinal cord anterior region has fewer parts of type primary motor neuron, abnormal trunk posterior region lacks all parts of type primary motor neuron, abnormal
	Fig. 4		smob641/b641 (AB)	pectoral fin hypoplastic, abnormal
	Fig. 6		smob641/b641 (AB)	eye adjacent to eye, abnormal
	Fig. 7		smob641/b641 (AB)	adenohypophyseal placode transformed to lens, abnormal eye lens deformed, abnormal forebrain dorsal/ventral pattern formation process quality, abnormal optic stalk physical object quality, abnormal retina development in camera-type eye process quality, abnormal
	Fig. 8		smob641/b641 (AB)	anterior commissure physical object quality, abnormal commissural neuron axon guidance process quality, abnormal forebrain axon guidance process quality, abnormal optic chiasm absent, abnormal optic stalk physical object quality, abnormal postoptic commissure absent, abnormal retinal ganglion cell axon guidance process quality, abnormal supraoptic commissure physical object quality, abnormal
Barresi et al., 2000	Fig. 2		smob577/b577 (AB) ,   smob641/b641 (AB)	muscle pioneer absent, abnormal slow muscle cell absent, abnormal slow muscle cell decreased amount, abnormal