FIGURE

Fig. 8

ID
ZDB-FIG-240221-19
Publication
Qin et al., 2023 - Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration
Other Figures
(all 9)
All Figure Page
Back to All Figure Page
Fig. 8

Knock-down of IDO1 abolished naringin-mediated suppression of fibrosis in zebrafish. (A) Molecular docking of Naringin and IDO1. (B) The qPCR analysis of IDO1 mRNA expression in zebrafish larvae (n = 3). (C) Sirius red staining of zebrafish larvae. Figures are magnified at ×200 (n = 8). (D) Oil red O staining of zebrafish larvae. Figures are magnified at ×100 (n = 8). (E) Frozen liver sections of zebrafish larvae with liver-specific eGFP expression were immunofluorescently stained with TGF-β and Desmin (n = 7). (F and G) The qPCR analysis of α-SMA and TNF-α mRNA expression in zebrafish larvae (n = 3). The mRNA expression was normalized to β-actin mRNA expression and presented as a fold change compared with the control group. ns denotes no significance, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Food Funct
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.