FIGURE

Fig. 6

ID

ZDB-FIG-240221-17

Publication

Qin et al., 2023 - Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration

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Fig. 6

Naringin reduced activation of inflammation and HSCs in TAA-induced liver fibrosis in zebrafish. (A) Naringin reduced the infiltration of macrophages in the alimentary canal of zebrafish during TAA exposure. Figures are magnified at 40× (n = 8). (B) Frozen liver sections of zebrafish larvae with liver-specific eGFP expression were immunofluorescently stained with desmin (n = 7). (C) Frozen liver sections of zebrafish larvae with liver-specific eGFP expression were immunofluorescently stained with TGF-β and NF-κB (n = 7). (D–G) The qPCR analysis of IDO1, TNF-α, IL-6, and IL-1β mRNA expression in zebrafish larvae (n = 3). The mRNA expression was normalized to β-actin mRNA expression and presented as a fold change compared with the control group. ns denotes no significance, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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