FIGURE

FIGURE 1

ID

ZDB-FIG-220924-1

Publication

Wareham et al., 2022 - Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development

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FIGURE 1

Ocular expression of adamts10 mRNA in zebrafish. (A) Expression of adamts10 mRNA (red dots, top row) was observed along the retinal pigment epithelium (dark brown/black structure) and dispersed throughout the retina of embryos at 24, 48, and 72 hpf. In 72 hpf eyes, robust signal (open arrowheads) extending from the inner retina and traversing a gap in the retinal pigmented epithelium (blue arrows, insert) is suggestive of optic nerve expression of adamts10 mRNA. (B) In 2-year-old adult eyes, expression of adamts10 mRNA was found in the outer nuclear layer (ONL), inner nuclear layer (INL), and ganglion cell layer (GCL). Hybridization probe against DapB, a bacterial gene, served as negative control on adjacent sections (bottom rows, A and B). Scale bar: 50 µm. L, Lens.

Expression Data

Gene:	adamts10
Fish:	AB
Anatomical Terms:	presumptive retinal pigmented epithelium retinal ganglion cell layer retinal inner nuclear layer retinal outer nuclear layer retinal pigmented epithelium
Stage Range:	Prim-5 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Mol Biosci