FIGURE

Figure 1

ID

ZDB-FIG-211025-8

Publication

Cairns et al., 2021 - A mutant wfs1 zebrafish model of Wolfram syndrome manifesting visual dysfunction and developmental delay

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Figure 1

Phenotypic analysis of wfs1a^−/− and wfs1b^−/− zebrafish. (A) Zebrafish were imaged at 30, 50 and 80 hpf. Scale bars represent 1 mm. (B–D) Zebrafish length at 30 hpf (B), 50 hpf (C) and 80 hpf (D). (E,F) Zebrafish head-trunk angles at 50 hpf (E) and 80 hpf (F). Zebrafish length and head tail angle was measured using ImageJ and data plots represent mean ± SEM (n = 10). Statistical significance was determined by One-Way ANOVA with Bonferroni multiple comparisons. **p < 0.01; ***p < 0.001; hpf hours post-fertilisation, SEM standard error of the mean.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	wfs1a^{sa10021/sa10021} (AB) wfs1b^{sa16422/sa16422} (AB)
Observed In:	head trunk whole organism
Stage Range:	Prim-15 to Protruding-mouth

Phenotype Detail

Acknowledgments

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