FIGURE

Figure 1—figure supplement 2.

ID

ZDB-FIG-191230-1756

Publication

Swire et al., 2019 - Endothelin signalling mediates experience-dependent myelination in the CNS

Other Figures

All Figure Page

Back to All Figure Page

Figure 1—figure supplement 2.

Social isolation reduces oligodendrocyte generation in the mPFC.

(A) Distance travelled by mice during 5 min of exploration of the social interaction assay. Grouped 15.48 meters ± 3.326 n = 12 mice, Isolated 16.15 meters ± 3.57 n = 9 mice (mean ± standard deviation). (B) Maximum speed travelled by mice during 5 min of exploration of the social interaction assay. Grouped 0.2433 ± 0.04117 n = 12 mice, Isolated 0.2619 meters ± 0.02792 n = 9 mice (mean ± standard deviation). (C) Quantification of CNP positive cells in medial prefrontal cortex layers II/III: Grouped 7709 ± 378.7 n = 5 mice, Isolated 4738 ± 385.7 n = 4 mice (mean ± standard error). (D) Quantification of CNP positive cells in medial prefrontal cortex layer V: Grouped 18879 ± 1559 n = 9 mice, Isolated 13099 ± 1052 n = 9 mice (mean ± standard error). (E) Mean myelin sheath length formed by oligodendrocytes per mouse. Grouped 46.10 µm ± 2.485 n=seven mice, Isolated 51.48 µm ± 4.08 n=four mice (mean ± standard error). (F) Frequency distribution of myelin sheath lengths.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife