FIGURE

Fig. 2

ID

ZDB-FIG-171113-47

Publication

Kotb et al., 2016 - Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin

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Fig. 2

APOL1 expression in human and zebrafish glomeruli.

The expression of APOL1 in podocytes is shown by double staining with an antibody against APOL1 and an antibody against the podocyte-specific proteins synaptopodin and nephrin (A-H). The regions in panel D and H labeled by arrows are shown in higher magnifications (insets). Similar to the human kidney, zApoL1 colocalizes with zNephrin in the zebrafish glomerulus (L). Panel M shows the localization of zApoL1 in podocytes (red circles) and in endothelial cells (green circles) by immunoelectron microscopy. Panel N shows the control reaction (secondary antibody only). Scale bars represent 20 μm (A-L) and 1 μm (M-N).

Expression Data

Genes:	apol1 nphs1
Antibody:	Ab2-apol1
Fish:	AB
Anatomical Terms:	pronephric podocyte pronephric podocyte podocyte foot pronephric podocyte podocyte primary projection
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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