FIGURE

Fig. S7

ID

ZDB-FIG-130411-2

Publication

Boglev et al., 2013 - Autophagy induction is a tor- and tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

Other Figures

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Fig. S7

Disruption of autophagy in tti^s450 larvae results in severe oedema. Upon microinjection into the yolk of 1–4 cell WT and tti^s450 zebrafish embryos, an atg5-targeted MO (1 ng) produces severe oedema around the organs of tti^s450 larvae at 120 hpf (D), while WT larvae are unaffected (C). WT and tti^s450 larvae injected at the 1–4 cell stage with vehicle (A, B) are also unaffected.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pwp2h^s450/s450 + MO1-atg5
Knockdown Reagent:	MO1-atg5
Observed In:	eye head heart intestine
Stage:	Day 5

Phenotype Detail

Acknowledgments

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