FIGURE

Fig. 6

ID

ZDB-FIG-120216-67

Publication

Yoruk et al., 2012 - Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease

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Fig. 6

stk25b overexpression in ccm3a/b morphants rescues ccm3a/b cardiovascular phenotype. Confocal z-stack projections of dorsal head vasculature in stk25b RNA (200 pg) injected and non-injected ccm3a/b morphants (0.5 ng ccm3a/b MO). Enlargement of the PrA and AceV in the vasculature were decreased in 68% of ccm3a/b morphants upon injection of stk25b mRNA (A–D, yellow arrows, n = 82).

Expression Data

Gene:	EGFP
Fish:	s843Tg + MO1-pdcd10a,pdcd10b
Knockdown Reagent:	MO1-pdcd10a,pdcd10b
Anatomical Term:	cranial vasculature
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s843Tg + MO1-pdcd10a,pdcd10b
Knockdown Reagent:	MO1-pdcd10a,pdcd10b
Observed In:	anterior cerebral vein prosencephalic artery
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 362(2), Yoruk, B., Gillers, B.S., Chi, N.C., and Scott, I.C., Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease, 121-131, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.