FIGURE

Fig. S5

ID

ZDB-FIG-080604-12

Publication

Postel et al., 2008 - Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex

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Fig. S5

Morpholino mediated knockdown of itga7 or ilk causes retraction of the complete skeletal muscle cell.
A,B) 3D reconstructions of confocal images showing retracted muscle fibres with membrane localized eGFP (green) and f-actin (phalloidin stain in red). Muscle fibre retractions were induced by morpholino knockdown of itga7 (A) or ilk (B). Arrows indicate retracted muscle fibres.

Expression Data

Gene:	EGFP
Fish:	vu119Tg + MO2-ilk vu119Tg + MO2-itga7
Knockdown Reagents:	MO2-ilk MO2-itga7
Anatomical Term:	skeletal muscle cell sarcolemma
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vu119Tg + MO2-ilk vu119Tg + MO2-itga7
Knockdown Reagents:	MO2-ilk MO2-itga7
Observed In:	skeletal muscle cell actin cytoskeleton skeletal muscle cell sarcolemma
Stage:	Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 318(1), Postel, R., Vakeel, P., Topczewski, J., Knöll, R., and Bakkers, J., Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex, 92-101, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.