FIGURE

Fig. 2

ID

ZDB-FIG-080604-2

Publication

Postel et al., 2008 - Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex

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Fig. 2

Ilk–GFP cellular localization. (A,B) Whole mount ISH with dig-labelled antisense ilk mRNA at 15-somite stage (A and inset) and 24 hpf (B). Wt embryos injected with synthetic mRNA encoding GFP–ILK (C and D) or memGFP (E and F). Images were taken at the 10-somite stage (15 hpf) at the region of the forming somites. The GFP–Ilk protein shows a predominant cytoplasmic localization at this stage. (G,H) Uninjected wt embryo (G) and a wt embryo injected with synthetic mRNA encoding GFP–Ilk (H) at 24 hpf. GFP–Ilk protein localization at the somite boundaries is indicated by arrowheads. (I,J) Anti-paxillin antibody staining and confocal images of a wt embryo (I) or loc/ilk mutant embryo (J) at 3 dpf.

Expression Data

Genes:	EGFP ilk pxna
Antibody:	Ab1-pxn
Fish:	WT ilk^hu801/hu801 vu119Tg
Anatomical Terms:	myoblast plasma membrane somite somite border muscle tendon junction
Stage Range:	10-13 somites to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 318(1), Postel, R., Vakeel, P., Topczewski, J., Knöll, R., and Bakkers, J., Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex, 92-101, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.