FIGURE

Fig. S6

ID

ZDB-FIG-071227-27

Publication

Esguerra et al., 2007 - Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination

Other Figures

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Fig. S6

Smad3b morpholino knockdown phenotype. Live observation of control^MO or Smad3b^MO embryos at 30 hpf. (A,A′) Wild-type embryo possesses normal morphology and clearly visible floorplate (fp, arrow). (B,B′) Smad3b morpholino-treated embryo displays anterior truncations, a curved shortened body axis, absence of floorplate, and a slightly enlarged intermediate cell mass (ICM, blue arrowhead), the latter phenotype indicative of partial ventralization. This phenotype was observed at 4 ng and 8 ng MO doses. Lateral views, anterior to the left, dorsal at top. Note: embryo in (B) is a composite photo to show all structures of embryo in focus.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-smad3b
Knockdown Reagent:	MO1-smad3b
Observed In:	floor plate head anterior-most region intermediate cell mass of mesoderm whole organism
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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