FIGURE

Fig. 9

ID

ZDB-FIG-240816-13

Publication

Bertho et al., 2021 - Zebrafish dazl regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition

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Fig. 9

Zygotic dazl mutants are sterile males. (A-C) Overall morphology of representative adult wild-type female (A), male (B) and dazlΔ7/ae57 compound heterozygote (C). Males and females are distinguished based on secondary sex traits (color and tubercles on male fins). (D-F) Dissected trunks with the gonad region, indicated with yellow dashed lines, of wild-type female (D), male (E) and dazlΔ7/ae57 compound heterozygote (F). (D′-F′) Higher magnification views of blue outlined region in D-F. (D′,E′) Oocytes in females (D′) and sperm/testicular structures of males (E′). No identifiable gametes or GCs were detected in compound heterozygotes (F′). (G-I) Gonads labeled with Vasa reveal the oocytes (G), spermatocytes (H) and a gonad lacking GCs (I).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dazl^ae57/+; dazl^mu12/+
Observed In:	female organism gamete germ line cell gonad male organism whole organism
Stage Range:	Days 45-89 to Adult

Phenotype Detail

Acknowledgments

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