FIGURE

Fig. 6

ID

ZDB-FIG-231023-27

Publication

Keseroglu et al., 2023 - Stochastic gene expression and environmental stressors trigger variable somite segmentation phenotypes

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Fig. 6

Embryotoxic chemicals worsen segmentation defects.

a, b Number of defective boundaries per each side of wild-type (WT) and her1^ci302 mutants treated with 3 µM DMSO (a, b, gray) (n = 172, N = 3, and n = 156, N = 3), 3 µM IPA-3 (a, green) (n = 138, N = 3, and n = 172, N = 3), and 3 µM SB225002 (b, purple) (n = 110, N = 3, and n = 168, N = 3). ****P < 0.0001 × 10⁻¹¹ (WT DMSO vs WT IPA-3), ****P < 0.0001 × 10⁻¹¹ (WT DMSO vs her1^ci302 DMSO), ****P < 0.0001 × 10⁻¹¹ (WT IPA-3 vs her1^ci302 IPA-3), ****P < 0.0001 × 10⁻¹¹ (her1^ci302 DMSO vs her1^ci302 IPA-3), ****P < 0.0001 × 10⁻¹¹ (WT DMSO vs WT SB225002), ****P < 0.0001 × 10⁻¹¹ (WT DMSO vs her1^ci302 DMSO), ***P = 0.0001 (WT SB225002 vs her1^ci302 SB225002), ****P = 0.4647 × 10⁻¹¹ (her1^ci302 DMSO vs her1^ci302 SB225002), Kruskal–Wallis ANOVA with Dunn’s multiple-comparison correction. The violin plots show the median (thick black line) and quartiles (thin black lines). n is the number of sides; N is the number of independent experiments. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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