FIGURE

Figure 5.

ID

ZDB-FIG-231019-12

Publication

Torraca et al., 2023 - Shigella serotypes associated with carriage in humans establish persistent infection in zebrafish

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Figure 5.

Shigella O-antigen serotypes associated with MSM transmission enable persistent infection. A and B, Percentage of larvae carrying persistent infection at 144 hpi and average bacterial log₁₀CFU for several S. flexneri isolates from serotypes 2a, 3a, and 5a. S. flexneri isolates of serotypes 2a and 3a are both capable of establishing persistent infection, to a much greater extent than S. flexneri of serotype 5a. C and D, Percentage of larvae carrying persistent infection at 144 hpi and average bacterial log₁₀CFU for S. flexneri M90T (serotype 5a), S. sonnei 53G, and S. flexneri SRR12769770 (a 2020 clinical isolate of S. flexneri from serotype 5a). SRR12769770 does not show a significant difference in the establishment of persistent infection when compared with S. flexneri M90T. Data: mean ± SEM. Statistics: 1-way analysis of variance with Sidak correction on (A, C) percentage data or (B, D) log₁₀-transformed data. ns, P ≥ .05. **P < .01. ***P < .001. ****P < .0001. CFU, colony-forming unit; hpi, hours postinfection; MSM, men who have sex with men; ns, nonsignificant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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