Fig. 2

Photic stimulation leads to model‐dependent change in swim velocity. (A) Mean swim velocity in response to 10‐s photic stimulation with 5‐min interstimulus interval. Each line in heatmaps represents the average across five trials for one fish. Dashed lines indicate the start and end of photic stimulation. (B) Mean swim velocity per subgroup. Gray shaded area indicates photic stimulation. (C) Light‐on amplitude measured as maximum change in velocity during the first 5 s after light onset. (D) Light‐off amplitude measured as the maximum change in velocity during the first 5 s after light offset. Total sample size for pentylenetetrazole (PTZ) model: control, n = 42; 1 mmol·L⁻¹, n = 42; 5 mmol·L⁻¹, n = 41; 15 mmol·L⁻¹, n = 41; for gabra1 model: wild‐type (wt), n = 39; heterozygous (het), n = 81; homozygous (hom), n = 48; for eaat2a model: wt, n = 11; het, n = 41; hom, n = 42. *p < .05, **p < .01 by Wilcoxon rank‐sum test. Shaded regions associated with individual colors represent SEM of each group. Boxplots represent median with interquartile ranges; whiskers extend to the most extreme data points that are not outliers