FIGURE

FIGURE 6

ID

ZDB-FIG-221227-6

Publication

Sun et al., 2022 - Craniofacial and cardiac defects in chd7 zebrafish mutants mimic CHARGE syndrome

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FIGURE 6

Expression of pdgfrb:GFP in craniofacial cartilages. (A) pdgfrb:GFP (pseudo-colored magenta) expression level is higher in the posterior part of the ceratohyal. 20X confocal stacked images, number of stacks n = 7, interval = 12 µm. (B) Representative images for the normal and abnormal basihyal in chd7 ^sr5 mutant fish. The abnormal one has extra cartilage near the basihyal cartilage, which expresses more pdgfrb:GFP compared to the basihyal cartilage and the nearby ceratohyal. sox10:switch (pseudo-colored yellow) labels NCCs. The white asterisks mark the extra cartilage. 20X single-slice confocal image. ch: ceratohyal; bh: basihyal (the number of fish with extra cartilage: WT: 0 in 6, chd7 ^+/sr5: 1 in 13, and chd7 ^sr5: 4 in 14). Scale bar = 50 µm for all images.

Expression Data

Gene:	EGFP
Fish:	ncv22Tg
Anatomical Terms:	basihyal cartilage ceratohyal cartilage cranial cartilage
Stage:	Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol