FIGURE

Fig. 7.

ID

ZDB-FIG-220317-14

Publication

Serrano et al., 2021 - Novel pre-clinical model for CDKL5 Deficiency Disorder

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Fig. 7.

Alcian Blue staining of craniofacial cartilage structures in cdkl5^−/− fish. (A) Dorsal and ventral images of Alcian Blue staining in cdkl5^+/+ and cdkl5^−/− fish at 7 dpf. aud, auditory capsule; cb, ceratobranchials or gill arch derivatives; ch, ceratohyal; eth, ethmoid plate; hys, hyosymplectic; mk, Meckel's cartilage; pec fin, pectoral fins; qu, quadrate. Scale bars: 100 µm. (B) Schematic of Alcian Blue staining in zebrafish heads at 7 dpf, showing locations of head measurements. (C) Quantification of the length (M1) and intersecting angle (M2) of the ceratohyal cartilage structures in cdkl5^+/+ and cdkl5^−/− fish at 7 dpf. Data are mean±s.d. (n=13 fish per genotype), *P<0.05, **P<0.01 (two-tailed t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdkl5^{sa21938/sa21938}
Observed In:	ceratohyal cartilage
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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