FIGURE

Fig. 6.

ID

ZDB-FIG-220317-13

Publication

Serrano et al., 2021 - Novel pre-clinical model for CDKL5 Deficiency Disorder

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6.

Brain imaging in cdkl5^−/− fish. (A) Maximum intensity projections of confocal images from whole brains from Tg(HuC:EGFP); cdkl5^+/+ and Tg(HuC:EGFP); cdkl5^−/− fish at 6 dpf. Scale bars: 100 µm. (B,C) Quantification of total brain (B) and cerebellar (C) volume from cdkl5^+/+ and cdkl5^−/− fish. Data are mean±s.e.m. for three independent experiments (n=12, 12 and 11 for cdkl5^+/+, and n=12, 12 and 12 for cdkl5^−/− fish), **P<0.01 (two-tailed t-test). 1 voxel=8 µm³.

Expression Data

Gene:	EGFP
Fish:	knu3Tg cdkl5^{sa21938/sa21938}; knu3Tg
Anatomical Term:	brain neuron
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdkl5^{sa21938/sa21938}; knu3Tg
Observed In:	brain cerebellum
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.