FIGURE

Figure 5

ID

ZDB-FIG-200805-11

Publication

Grivas et al., 2020 - Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart

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Figure 5

Cardiomyocyte proliferation is transiently reduced upon cryoinjury in cav1^cn100 hearts. (a, b) Immunolabelling of 7 dpci cav1^+/+ and cav1^cn100 hearts for BrdU, MEF2 and MF20. (a′, b′) Magnifications of the dashed areas in (a) and (b). (c) Cardiomyocyte proliferation rate was measured by quantifying the BrdU⁺/MEF2⁺ nuclei to the total cardiomyocyte number in a 100 μm radius around the injured area. CM, cardiomyocytes. n_WT = 5, n_cn100 = 6, t-test, **P < 0.01. (d, e) Immunostaining of 14 dpci cav1^+/+ and cav1^cn100 hearts for BrdU, MEF2 and MF20. (d′, e′) Magnifications of the dashed areas in (d) and (e). (f) Quantification of cardiomyocyte proliferation at 14 dpci. n_WT = 7, n_cn100 = 4, t-test. Scale bars: 100 μm in (a), (b), (d), (e); 10 μm in (a′), (b′), (d′), (e′).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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