FIGURE

Figure 10

ID

ZDB-FIG-200713-28

Publication

Coomer et al., 2020 - Her9/Hes4 is required for retinal photoreceptor development, maintenance, and survival

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Figure 10

Her9 mutants display abnormal expression of photoreceptor lineage genes. (A–B′) Fluorescent in situ hybridization (FISH) for crx at 48 hpf in WT and mutant neural retina. (C) Crx sense probe. (D–E′) Decreased expression of Nr2e3 in the mutant retina compared to the wildtype. (F) Nr2e3 sense probe. (G,H) Whole mount in situ hybridization (WISH) for thrβ expression at 48 hpf in WT and her9 mutant retina. thrβ expression in her9 mutants displayed a decreased and patchy or abnormal pattern. (I) χ² analysis comparing WT incross and her9 heterozygous incross expression pattern. (J) qPCR for thrβ at 48 and 72 hpf. L, lens. Scale bar = 50 µm.

Expression Data

Genes:	crx nr2e3 thrb
Fish:	WT her9^uky2/uky2
Anatomical Terms:	retina retina ventral region retinal outer nuclear layer whole organism
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	her9^uky2/uky2
Observed In:	retina retina ventral region retinal cone cell fate specification retinal outer nuclear layer whole organism
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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