FIGURE

Figure 5

ID

ZDB-FIG-200125-59

Publication

Matchett et al., 2019 - Paralogues of Mmp11 and Timp4 Interact during the Development of the Myotendinous Junction in the Zebrafish Embryo

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Figure 5

Timp4 and both Mmp11 paralogues are present in the MTJ at 28 hpf. High-resolution confocal micrographs of MTJs in the trunk skeletal musculature dorsal to the yolk extension of 28 hpf embryos stained with antibodies against (A) Mmp11a, (B) Mmp11b, (C) Timp4, and (D) Laminin (green) as well as anti-α-actinin (red) reveal that both Mmp11 paralogues are detectable in MTJs at this stage, and that they accumulate in the periphery of the MTJ (arrowheads), whereas Timp4 accumulates in the core of the MTJ. Scale bars are 10 µm. Anterior to the left in all images.

Expression Data

Genes:	mmp11a mmp11b
Antibodies:	Ab1-actn Ab1-mmp11a Ab1-mmp11b Ab1-timp4 Ab9-lam
Fish:	TU
Anatomical Terms:	myotome Z disc vertical myoseptum central region vertical myoseptum peripheral region
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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