FIGURE

Fig. 1

ID

ZDB-FIG-171117-1

Publication

Lee et al., 2016 - Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

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Fig. 1

Expression of Myc and Fgf pathway genes during HC regeneration in zebrafish neuromasts by in situ hybridization.

mycb (A-D), fgf10a (E-H), fgf3 (I-L), fgfr1a (M-O), fgfr2 (P-R) expression were shown in the lateral line neuromast L1 from 5-dpf zebrafish at different time points following neomycin treatment (e.g. Neomycin-6hr, 6 hrs after neomycin treatment). Ctr, untreated fish larvae. Dotted blue lines marked the boundary of neuromasts. Bold dotted lines marked the expression areas (M,O,P,R). (S) An illustration of a neuromast demarcated by differential fgfr expression patterns, including HC region, fgfr1a(+) only region, fgfr1a/r2(+) region and fgfr1a(-) region. A-P, anterior-posterior; D-V, dorsal-ventral. Scale bars: 10 μm.

Expression Data

Genes:	fgf3 fgf10a fgfr1a fgfr2 mycb
Fish:	AB
Condition:	chemical ablation: neuromast hair cell, chemical treatment by environment: neomycin
Anatomical Terms:	anatomical structure neuromast hair cell neuromast support cell
Stage Range:	Day 5 to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical ablation: neuromast hair cell, chemical treatment by environment: neomycin
Observed In:	neuromast hair cell neuromast support cell
Stage Range:	Day 5 to Day 6

Phenotype Detail

Acknowledgments

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