FIGURE
Fig. S4
- ID
- ZDB-FIG-170609-46
- Publication
- Theodore et al., 2017 - Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization
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Fig. S4
Mmp2 inhibition causes an accumulation of fibronectin in the AGM. Related to Figure 4. A) Exposure to SB-3CT (10μM, 32-48 hpf) increased fibronectin staining in the AGM compared to controls at 48 hpf (n≥10 embryos/condition). B) Vibratome cross-sections show increased fibronectin staining in the posterior cardinal vein (PCV) and ventral wall of the dorsal aorta (DA) with SB-3CT treatment (32-54 hpf) compared to controls; inset magnifications of boxed regions (from left panels) show gray-scale fluorescence of fibronectin (right; n≥7 embryos/condition). Scale bars: 30 (A) and 15μm (B). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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