FIGURE

Fig. 4

ID

ZDB-FIG-151208-17

Publication

Jensen et al., 2015 - VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish

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Fig. 4

mRNA expression levels of Vegfa, Vegfb, and Vegfrs in developing zebrafish embryos. (A) In situ hybridization micrographs of Vegfba, Vegfaa, Vegfr1, Nrp1, Vegfr2a, or Vegfr2b expression in 24-hpf zebrafish embryos. In situ positive signals are in dark blue. White arrows indicate MCVs (Vegfr1, Nrp1, Vegfr2a, and Vegfr2b images) or the MCV area (Vegfba and Vegfaa images). Red arrows indicate somites (Vegfaa) or ISVs. (Scale bar in overview: 500 µm; in brain: 200 µm; in periphery: 100 µm.) (B) In situ hybridization micrographs of Vegfba or Vegfaa expression in the brain or peripheral trunk regions of zebrafish embryos at 24, 30, 36, 42, or 48 hpf. In situ positive signals are in dark blue. White arrows indicate the MCV area. Red arrows indicate the peripheral expression-pattern of Vegfaa mRNA. (Scale bars in the brain, 200 µm; in periphery, 100 µm.)

Expression Data

Genes:	flt1 kdr kdrl nrp1b vegfaa vegfba
Fish:	WT
Anatomical Terms:	brain mid cerebral vein somite trunk vasculature
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA