FIGURE

Fig. 3

ID

ZDB-FIG-140915-13

Publication

Skobo et al., 2014 - Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development

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Fig. 3

Abnormal morphology of ambra1 knockdown embryos, as revealed by haematoxylin/eosin staining.

Representative longitudinal sections of 3 dpf control and ambra1 morphant embryos. Myofibers of ATG- and co-injected morphants muscles are highly disorganized and display irregular myosepta boundaries. The phenotype of splice-morphants is much less severe when compared to WT and 5 m-control embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-ambra1a AB + MO1-ambra1b AB + MO2-ambra1a AB + MO2-ambra1b AB + MO1-ambra1a + MO1-ambra1b
Knockdown Reagents:	MO1-ambra1a MO1-ambra1b MO2-ambra1a MO2-ambra1b
Observed In:	muscle cell muscle cell nucleus myoseptum
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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