FIGURE

Fig. 1

ID

ZDB-FIG-140811-37

Publication

Zhu et al., 2014 - Haploinsufficiency of Def Activates p53-Dependent TGFbeta Signalling and Causes Scar Formation after Partial Hepatectomy

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Fig. 1

def^+/- liver suffers from haploinsufficiency of Def.

(A) qPCR analysis of def transcripts in adult wild-type and def^+/- liver. The expression of def was normalised against elf1a and is shown as the fold change in expression, with the value from def^+/- being set at 1. The values plotted represent the means ± standard errors of the mean. (B) Western blotting analysis of the Def protein. Bhmt: loading control. Densitometry was performed using Photoshop. The value of Def was obtained by normalising against Bhmt expression. The relative value of Def protein in def^+/- was set at 1. (C) Representative images of immunostaining of Def (red) in wild-type and def^+/- liver 2 days after PH. lv, liver tissue. Scale bar: 100 μm (C).

Expression Data

Antibody:	Ab1-diexf
Fish:	WT utp25^hi429Tg/+
Condition:	physical alteration: anatomical structure
Anatomical Term:	liver nucleolus
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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