FIGURE

Fig. 3

ID

ZDB-FIG-140709-36

Publication

Feng et al., 2010 - Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism

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Fig. 3

In situ validation of microarray hits whose expression is increased in RA-treated embryos and reduced in antagonist-treated embryos. Dorsal views of eight selected microarray hits (blue) and egr2b (red) in situ at 11 hpf. Anterior is to the left in all panels. Column i: control (DMSO) treated; ii: 10 µM DEAB (RA synthesis antagonist) treated; iii: 0.33 µM RA-treated. The numbers in the upper right corners refer to the fold-change in expression level identified on the microarray under the corresponding conditions.

Expression Data

Genes:	egr2b hnf1bb myt1a nr2f6b nrip1b pgp rxrga spsb4a wnt11
Fish:	AB
Conditions:	chemical treatment: 4-(diethylamino)benzaldehyde chemical treatment: all-trans-retinoic acid
Anatomical Terms:	adaxial cell ectoderm hindbrain neural plate lateral mesoderm presumptive rhombomere 3 presumptive rhombomere 5 pronephric mesoderm somite unspecified whole organism whole organism anterior region
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 338(1), Feng, L., Hernandez, R.E., Waxman, J.S., Yelon, D., and Moens, C.B., Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism, 1-14, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.